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Symptoms of Rubella in newborns

Contingent upon while during the pregnancy the embryo is contaminated, it might have no indications or might be stillborn. Babies who endure may have various birth deserts. These birth absconds are alluded to as congenital rubella syndrome (CRS).  The most well-known indications of innate rubella disorder in infants incorporate: Low birth weight  Small head/ Microcephaly   Brain inflammation Cataracts Damage to the retina Hearing loss Heart defects Enlarged liver and spleen Bruises or other skin spots Enlarged lymph nodes
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Acrodermatitis enteropathica

 

Acrodermatitis enteropathica

This is a disorder due to zinc deficiency of various causes:

  • Inherited form - an autosomal recessive; rare condition due to defective intestinal absorption of zinc.
  • Acquired transient neonatal form due to nutritional zinc deficiency from:
    1. Breast-fed infants in mothers with low zinc levels.
    2. Premature infants with prolonged TPN.
    3. Infants with malabsorption (including cystic fibrosis).

Clinical features

  • The inherited form develops when weaned from breastfeeding (as breast milk contains a zinc ligand-binding protein and therefore helps zinc absorption) or earlier if bottle-fed.
  • Persistent well-demarcated rash:
    1. Nappy rash

    2. Around eyes and nose
    3. Involves the flexures
  • Failure to thrive, listlessness
  • Photophobia,diarrhoea,alopecia,nail dystrophy
  • Diagnosis - plasma zinc levels low ( <50 microgram per milliliter), alkaline phosphatase also low (zinc-dependent enzymes)
  • Rapid response to zinc supplementation

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